Hello, I'm Miko, the manager of Kokaiko Shoten!
Just the other day, we received some exciting news! Professor Shimon Sakaguchi of Osaka University was awarded the Nobel Prize in Physiology or Medicine.

Professor Sakaguchi discovered "regulatory T cells," which act as brakes on the immune system. His research is now bringing great hope for the treatment of autoimmune diseases, including type 1 diabetes.
In fact, what I want to talk about today is type 1 diabetes, which is one of these "autoimmune diseases."
Recently, we have heard that the number of people developing type 1 diabetes as adults is increasing. Many people may have wondered, "Isn't type 1 diabetes a hereditary disease that develops in childhood?"
However, in fact, numerous research findings have shown that the foods we eat every day are deeply connected to the mechanism that Professor Sakaguchi has been researching, which confuses the immune system and causes it to attack its own pancreas.
There are more than 200 clinical trials underway worldwide aimed at treating type 1 diabetes. If we can stop the immune system from going "out of control," we may one day be able to prevent or treat this disease.
However, as I have said many times before, medication is merely a symptomatic treatment. Even if you suppress the runaway immune system with medication, unless you remove the cause, you will have no choice but to suppress it with medication for the rest of your life.
No matter how many times I explain to you, "But type 1 diabetes is genetic!", you're right! Is it really genetic? If so, isn't it strange that the number of adult type 1 diabetes cases has suddenly increased?
So type 1 diabetes is no longer something that only affects other people.
So let's explain in more detail!
- Basic understanding of type 1 diabetes
- Autoimmune disease mechanism
- Why does it develop in adults?
- The relationship between wheat and TNFα (tumor necrosis factor α)
- The surprising connection between celiac disease and type 1 diabetes
- Increased intestinal permeability by gluten
- Overproduction of TNFα and misdirected attack on the pancreas
- Problems with modern wheat
- Dramatic improvement after eliminating wheat
- Is eliminating wheat the key to preventing type 1 diabetes?
- The link between artificial sweeteners and type 1 diabetes
- The effects of processed foods
- The relationship between maternal diet during pregnancy and type 1 diabetes in children
- DOHaD hypothesis: Prenatal life determines life
- A mother's intestinal environment shapes her baby's immune system
- If you eat wheat, artificial sweeteners, or processed foods during pregnancy...
- Shocking research results
- The lactation period is also important: effects through breast milk
- Postnatal diet: The first 1000 days are crucial
- What you can do now: Diet before, during and while breastfeeding
- It's not "It's genetic, so there's nothing I can do about it"
- Prevention and measures for adults
- From Kogaiko Shoten: Authentic Japanese Foods to Support a Healthy Body
- summary
Basic understanding of type 1 diabetes
Type 1 diabetes is a disease in which pancreatic beta cells are destroyed by an autoimmune reaction, resulting in little or no insulin secretion . It was once called "juvenile diabetes" and was thought to occur mainly in young people, but in recent years there has been a dramatic increase in adult-onset type 1 diabetes (LADA: Latent Autoimmune Diabetes in Adults), which has attracted attention in the medical community.
While type 1 diabetes was previously thought to be purely genetic, it is now clear that it develops as a result of a complex interplay of environmental factors. In particular, when it develops in children, some doctors now point out that the mother's eating habits during pregnancy play a significant role. It has also been pointed out that in adults, modern changes in dietary habits may be affecting the autoimmune system, increasing the risk of developing the disease in adulthood .
Autoimmune disease mechanism
The autoimmune response in type 1 diabetes occurs when the immune system, which is supposed to protect the body from foreign invaders, mistakenly attacks the body's own pancreatic beta cells. During this process, immune cells such as T cells and B cells are activated and produce autoantibodies that target insulin-producing cells.
One thing to be careful about is the term "insulin resistance." Insulin resistance is primarily a characteristic of type 2 diabetes and refers to a condition in which cells become less responsive to insulin. In contrast, type 1 diabetes is a condition in which insulin itself is not produced. However, adult-onset type 1 diabetes can sometimes be accompanied by insulin resistance in the early stages, making it difficult to distinguish from type 2 diabetes.
Why does it develop in adults?
There are several reasons why people develop type 1 diabetes in adulthood:
1. Slow progression
In adult-onset type 1 diabetes (LADA), the autoimmune response progresses more slowly than in childhood-onset diabetes. Because the destruction of pancreatic beta cells progresses slowly over several months to several years, symptoms are mild in the early stages and are often overlooked.
2. Accumulation of environmental triggers
The accumulation of environmental factors over many years can, at some point, exceed a threshold and trigger an autoimmune response . Research suggests that long-term exposure to chemicals, additives, and processed foods in the modern diet may be gradually damaging the immune system.
3. Changes in the intestinal environment
Changes in diet during adulthood, particularly the increased consumption of processed foods, disrupt the balance of the intestinal flora. Because the intestinal environment controls over 70% of the immune system, any disruption increases the risk of autoimmune diseases.

Type 1 diabetes
Wheat, artificial sweeteners, and processed foods are to blame
Recent research suggests that wheat (especially modern wheat varieties), artificial sweeteners, and processed foods may increase the risk of autoimmune diseases.
The relationship between wheat and TNFα (tumor necrosis factor α)
The possible role of modern wheat in the development of type 1 diabetes is a common and important issue among experts.
In fact, celiac disease is known as an autoimmune disease caused by wheat, and recent research has revealed a close connection between this disease and type 1 diabetes.
The surprising connection between celiac disease and type 1 diabetes
Celiac disease is an autoimmune disease in which wheat gluten destroys the mucous membrane of the small intestine. Surprisingly, the incidence of celiac disease among type 1 diabetes patients is several to several times higher than that of the general population .
According to one study, there is data that shows that about 10 to 20 times more children with type 1 diabetes also have celiac disease. Conversely, it has been reported that the incidence of type 1 diabetes in patients with celiac disease is significantly higher than normal. These two diseases often appear as a set.
Even more noteworthy, research has shown that feeding wheat to children under the age of four increases their risk of type 1 diabetes, and that the risk is even higher in children who are given wheat as infants under the age of six months.
Increased intestinal permeability by gluten
It has been shown that gluten (particularly gliadin) in wheat stimulates the secretion of a substance called zonulin, which increases intestinal permeability, allowing undigested proteins and bacterial fragments that should not enter the bloodstream to enter the body.
This condition is called "leaky gut syndrome," and destruction of the intestinal barrier is prominent in patients with celiac disease. It is believed that this destruction of the intestinal barrier is the trigger for various autoimmune diseases, including type 1 diabetes.
Overproduction of TNFα and misdirected attack on the pancreas
When the intestinal barrier is disrupted, the immune system overreacts, producing large amounts of pro-inflammatory cytokines such as TNFα (tumor necrosis factor alpha). TNFα is an important substance for fighting infections and tumor cells, but chronic high levels of production confuse the immune system, causing it to mistakenly attack its own tissues.
Autoimmune diseases vary depending on the target they attack
Interestingly, even if the mechanism is the same (destruction of the intestinal barrier → runaway immune system), which organs and tissues are attacked varies depending on the individual's constitution and genetic predisposition:
- Attacks pancreatic beta cells → Type 1 diabetes
- Attacks the large intestine → Crohn's disease, ulcerative colitis
- Attacks the skin → atopic dermatitis, psoriasis, palmoplantar pustulosis
- Attacks joints → rheumatoid arthritis
- Attacks the thyroid gland → Hashimoto's disease (hypothyroidism), Graves' disease (hyperthyroidism)
- Attacks the myelin sheath of nerves → multiple sclerosis
- Attacks the mucous membrane of the small intestine → Celiac disease
- Attacks pigment cells in the skin → Vitiligo vulgaris
- Attacks muscles → polymyositis, dermatomyositis
- Attacks salivary glands and lacrimal glands → Sjögren's syndrome
- Attacks blood vessels → vasculitis syndrome
- Attacks red blood cells → autoimmune hemolytic anemia
- Attacks platelets → Idiopathic thrombocytopenic purpura
- Attacks the kidneys → IgA nephropathy, lupus nephritis
- Attacks the liver → autoimmune hepatitis, primary biliary cholangitis
What all of these diseases have in common is that their root cause is a breakdown of the intestinal barrier and a disruption of the immune system . In other words, even though the names of the diseases are different, they all start from the same point: a deterioration of the intestinal environment caused by food.
That's why it's not uncommon for people with autoimmune diseases to also have multiple other conditions: for example, people with type 1 diabetes often also have celiac disease and thyroid disease, and people with rheumatoid arthritis often also have Sjögren's syndrome.
One person may have multiple autoimmune diseases
In fact, there is data that shows that people with one autoimmune disease have a risk of developing another autoimmune disease several times to several dozen times higher than the average person. This indicates that unless the fundamental problem of the "runaway immune system" is resolved, there is a possibility that the targets of attack will continue to increase.
In other words, even though the names and symptoms of the diseases may differ, the essential solution is the same : to improve the intestinal environment and normalize the immune system. To achieve this, it is most important to avoid foods that destroy the intestinal barrier, such as wheat, artificial sweeteners, and processed foods, and to strive for a diet as close to natural as possible.
Problems with modern wheat
Modern wheat, which has been selectively bred since the 1960s, has an increased gluten content and a structure that makes it difficult to digest, which increases the burden on the intestinal tract and makes it more likely to cause an inflammatory response.
Compared to wheat of the past, modern wheat has been extensively bred to increase yield, resulting in a more complex gluten structure. Many researchers point out that this "new wheat" poses an unknown burden to the human digestive system, possibly contributing to an increase in autoimmune diseases.
Related Article - Should you avoid wheat flour? A veteran with 20 years of experience working at a flour mill shares the unknown truth about wheat flour
Dramatic improvement after eliminating wheat
In fact, some people who have been diagnosed with celiac disease and have followed a gluten-free diet that completely eliminates wheat have been reported to have been able to prevent or improve diabetes.
One study showed that when celiac disease patients completely eliminated wheat, the incidence of diabetes significantly decreased from 64% to 15% , strongly suggesting that wheat triggers an autoimmune response that is directly involved in the development of diabetes.
The mother's diet during pregnancy is also important. It has been pointed out that if a mother consumes large amounts of wheat products during pregnancy, the child may be at a higher risk of developing type 1 diabetes in the future. This is because the mother's intestinal environment and immune status affect the development of the fetus's immune system.
Is eliminating wheat the key to preventing type 1 diabetes?
These findings have led some experts to argue that eliminating wheat from the diet may help prevent type 1 diabetes .
Especially if you're a strong believer in genetics and have family members with type 1 diabetes, or if your children show signs of an autoimmune response, it might be worth trying a wheat-free diet, part of the much-needed answer to preventing potentially lifelong type 1 diabetes.
Related article - The real reason why cholesterol levels don't go down: The scientific mechanism by which your body changes just by giving up wheat
The link between artificial sweeteners and type 1 diabetes
Along with wheat, artificial sweeteners have been linked to a higher risk of type 1 diabetes. While artificial sweeteners such as aspartame, sucralose, acesulfame K, and saccharin are widely used with appealing terms like "zero calories" and "low sugar," they can have serious effects on the pancreas and immune system.
Destruction of the intestinal flora and runaway immunity
A 2014 study published in Nature showed that artificial sweeteners dramatically alter the gut microbiome, most importantly:
- Decrease in beneficial bacteria : Beneficial bacteria that regulate the immune system, such as bifidobacteria and lactobacillus, are significantly reduced
- Disruption of the intestinal barrier : Like wheat gluten, it destroys the intestinal "wall" and causes leaky gut syndrome.
- Decline in regulatory T cell function : The immune "brake" discovered by Professor Sakaguchi no longer works
This disruption of the intestinal environment leads to the overproduction of inflammatory cytokines such as TNFα, which triggers the immune system to attack pancreatic beta cells.
Direct damage to pancreatic beta cells
The most insidious thing about artificial sweeteners is that they trick your body with just the sweet taste signal:
- The tongue feels sweet
- The brain determines that sugar has entered the body
- The pancreas begins to secrete insulin
- However, since there is no carbohydrate in reality,
- Repeated "spinning" causes the pancreas to become exhausted
Furthermore, research has shown that artificial sweeteners such as aspartame can exert direct oxidative stress on pancreatic beta cells, potentially leading to cell death.
Artificial sweetener intake during pregnancy and its effects on the baby
Like wheat, maternal consumption of artificial sweeteners during pregnancy is also a major concern:
- Adversely affects the development of fetal intestinal flora
- Impairs the development of children's immune systems
- Increased risk of developing type 1 diabetes in the future
Studies have shown that babies born to mothers who regularly consumed artificially sweetened drinks during pregnancy are at higher risk of metabolic and immune system problems.
Wheat and artificial sweeteners: a 'terrible combination'
Even more serious is the combination of wheat and artificial sweeteners:
- "Diet" bread (wheat + artificial sweeteners)
- Low-carb sweets (wheat flour + artificial sweeteners)
- Protein Bar (Wheat + Artificial Sweeteners)
These foods double-destroy the intestinal barrier and accelerate the immune system's rampage. We need to be aware of the dangers hidden behind the advertising claims of "healthy" and "low-carb."
In fact, many people who have completely eliminated artificial sweeteners and wheat have reported dramatic improvements in unexplained fatigue and inflammatory symptoms.
Are natural sweeteners safe?
Some people say, "Artificial sweeteners are dangerous, so I use natural sweeteners like stevia and erythritol," but you should be careful.
These "natural" sweeteners can also affect the intestinal flora if consumed in excess. In particular, sugar alcohol sweeteners (erythritol, xylitol, etc.) can ferment in the intestines, producing gas and causing diarrhea and abdominal pain.
The safest option is to reduce your reliance on sweeteners and rediscover the satisfying sweetness of natural foods .
The effects of processed foods
Along with wheat and artificial sweeteners, modern processed foods as a whole are major factors that increase the risk of type 1 diabetes. However, the most serious problem is not the danger of individual additives, but the fact that the effects of multiple additives combined have not been examined at all .
The unknown horror of the "cocktail effect"
Safety testing of food additives is generally conducted on each type individually.
- Preservative A → Safe within standard limits
- Coloring agent B → Safe and within the standard limits
- Emulsifier C → Safe within standard limits
However, no one has ever examined the impact of multiple combinations, such as A + B + C + D + E...
The processed foods we eat every day contain an average of more than 10 types of additives. If you add up convenience store bento boxes, instant foods, soft drinks, and sweets, you will be consuming dozens of types of additives every day.
When it comes to medicines, doctors carefully check for drug interactions, but when it comes to food additive interactions, they are left unchecked.
A combined attack on the intestinal barrier
Processed foods contain many different compounds that attack your gut simultaneously:
Emulsifiers (polysorbate 80, carboxymethylcellulose) → Directly destroy the intestinal mucosal barrier
Preservatives (sodium benzoate, potassium sorbate) -> Kill good bacteria in the intestines and increase bad bacteria
Coloring agents (tar-based pigments) → stimulate the immune system
Trans fats, refined sugars, and excess salt lead to chronic inflammation
The simultaneous presence of these factors accelerates the breakdown of the intestinal barrier and synergistically amplifies the effects on the immune system, resulting in the excessive production of inflammatory cytokines such as TNFα, which initiates an attack on pancreatic beta cells.
High-temperature cooking and AGEs (advanced glycation end products)
Furthermore, processed foods cooked at high temperatures contain large amounts of harmful substances called AGEs. AGEs increase oxidative stress and directly damage pancreatic beta cells. These AGEs may also act in conjunction with other additives, further increasing their harmful effects.
Worst Combo: Triple Whammy
The greatest danger is consuming wheat, artificial sweeteners, and processed food additives at the same time .
For example, one piece of commercially available bread contains:
- Wheat (gluten) → Destroys the intestinal barrier
- Artificial sweeteners destroy the intestinal flora
- Emulsifiers → further destroy the intestinal mucosa
- Preservatives : Kill good bacteria
- pH adjuster, yeast food, flavoring... → Interactions unknown
The combined impact of these factors is immeasurable.
Children and pregnant women should be especially careful
Consuming processed foods on a daily basis is particularly dangerous for growing children and pregnant mothers, as additives can damage a child's immature intestinal tract and disrupt their developing immune system, increasing their risk of developing type 1 diabetes later in life.
Dramatic changes in people who avoid processed foods
In fact, people who have completely eliminated processed foods report:
- Unexplained chronic fatigue disappeared
- Dramatically improved intestinal health
- Reduced inflammatory markers throughout the body
- Improved blood sugar control
This is the result of being freed from complex pollution, restoring the intestinal barrier, and normalizing the immune system.
The most important thing you can do to prevent type 1 diabetes is to avoid wheat, artificial sweeteners, and processed foods in general, and choose foods that are as close to natural as possible.
The relationship between maternal diet during pregnancy and type 1 diabetes in children
In fact, it is now believed that the onset of type 1 diabetes begins while the baby is still in the womb . For many years, it was thought that type 1 diabetes in children was hereditary, but it is possible that this is actually a legitimate food-related disease.
DOHaD hypothesis: Prenatal life determines life
The "DOHaD (Developmental Origins of Health and Disease) hypothesis" -- known in Japanese as the "Fetal Origins of Adult Diseases" -- is a theory that is currently attracting attention in the medical community.
Simply put, this is the idea that the environment a baby experiences in its mother's womb greatly influences its health after birth . The nutritional status and environment during fetal and infant stages determine the risk of illness in the future.
However, if you think about it, this is probably obvious, since the source of cell division during the period when cells are most active is what the pregnant mother ate.
A mother's intestinal environment shapes her baby's immune system
Amazingly, the foundation of a baby's immune system is formed by the mother's gut environment.
What happens during pregnancy:
- Mother's gut bacteria affect the fetus
Metabolic substances (such as short-chain fatty acids) produced by the mother's gut bacteria reach the fetus through the placenta, where they "educate" the developing fetus's immune system. - The immune status of the mother determines the immunity of the fetus
If the mother has chronic inflammation (due to wheat, artificial sweeteners, and processed foods), the inflammatory cytokines will affect the fetus, and the baby's immune system will be primed for "fighting mode" even while still in the womb. - The "tradition" of the intestinal flora
During birth, babies inherit their mother's intestinal bacteria as they pass through the birth canal. If the mother's intestinal environment is poor, the baby will also start out with a poor intestinal environment.
If you eat wheat, artificial sweeteners, or processed foods during pregnancy...
If a mother consumes large amounts of these foods during pregnancy, the following effects are of concern:
Effects on the fetal immune system
- Inadequate development of regulatory T cells (which act as brakes on the immune system)
- Becoming prone to producing autoantibodies
- Formation of an immune system prone to inflammatory responses
Malformation of the intestinal flora
- Start in an intestinal environment with few good bacteria and many bad bacteria
- The intestinal barrier is naturally weak
- Becoming more susceptible to leaky gut syndrome
Effects on pancreatic beta cells
- The pancreas is under strain from the fetal stage
- Beta cells become fewer in number or less functional
- Being at risk for type 1 diabetes from birth
Shocking research results
Wheat intake and type 1 diabetes in children under 4 years of age
As mentioned earlier, children who are fed wheat before the age of six months are at significantly increased risk of developing type 1 diabetes. However, it is possible that they may have been affected by wheat even before that – even while they were still in their mother's womb .
Artificial sweetener consumption during pregnancy and metabolic disorders in children
One study showed that babies born to mothers who drank artificially sweetened beverages daily during pregnancy were twice as likely to be obese by the age of one and also had a higher risk of developing glucose metabolism disorders later in life.
Processed food intake during pregnancy and autoimmune diseases
There is also data that shows that children whose mothers consumed a lot of processed foods during pregnancy have a higher incidence of immune-related diseases such as allergies, atopy, and asthma.
The lactation period is also important: effects through breast milk
Not only during pregnancy, but also during breastfeeding, your diet has a direct impact on your baby .
In breast milk:
- Immune substances derived from the mother's intestinal bacteria
- Ingredients of what the mother ate
- Antibodies that reflect the maternal immune status
Contains:
If a nursing mother regularly consumes wheat, artificial sweeteners, and processed foods, these effects can reach her baby through breast milk and disrupt the development of her baby's intestinal environment and immune system.
Postnatal diet: The first 1000 days are crucial
In the medical community, it is said that the period from conception to a child's second birthday (approximately 1,000 days) is the most critical period that determines a child's lifelong health .
During this period:
- Wheat products (bread, udon noodles, baby food such as bread porridge)
- Processed foods such as baby food
- Sugary drinks and artificially sweetened snacks
Feeding children puts a great strain on their immature intestines and immune systems.
In particular, using wheat products carelessly in baby food may increase the risk of type 1 diabetes, celiac disease, other autoimmune diseases, developmental disorders, and intellectual disabilities in the future .
Related article: The importance of improving your child's intestinal environment and effective ways to improve your intestinal health
What you can do now: Diet before, during and while breastfeeding
For those planning to become pregnant, pregnant, or breastfeeding
What you eat now can affect your child's health for the rest of their lives. Here are some things to keep in mind:
✓ Avoid wheat products (bread, pasta, udon, cake, etc.)
✓ Completely avoid artificial sweeteners (zero calorie drinks, diet foods, etc.)
✓ Avoid processed foods (convenience store bento, instant foods, snacks, etc.)
✓ Eat naturally fermented foods (miso, natto, pickled vegetables, etc.)
✓ Eat plenty of dietary fiber (vegetables, seaweed, mushrooms, etc.)
✓ Eat high-quality fats (naturally extracted oils, meat and fish as close to natural as possible, etc.)
It's not "It's genetic, so there's nothing I can do about it"
There is no need to give up just because "someone in my family has type 1 diabetes, so my child will too."
It is true that there may be some genetic predisposition, but this is simply a "constitution that is prone to the disease," and if you take measures, you will not get it. It has been proven that environmental factors pose a greater risk than genetics. Whether or not you actually develop the disease is greatly influenced by environmental factors, especially your diet .
By following a healthy diet before conception, during pregnancy, breastfeeding, and while your child is still on solid food, it is entirely possible to prevent the onset of type 1 diabetes, even if you have a genetic risk.
Your dining table will shape your children's future.
This is no exaggeration, but a scientifically proven fact.
The mother's diet during pregnancy is also an important consideration.
The "DOHaD (Developmental Origins of Health and Disease) hypothesis," which states that the nutritional environment during fetal and infant stages affects the risk of future autoimmune diseases, is attracting attention.
If a mother consumes large amounts of processed foods, wheat products, and artificial sweeteners during pregnancy, this can affect the development of the fetus's immune system and the formation of its intestinal flora .
Postnatal diet is also important, as early exposure to processed foods and artificial sweeteners has been shown to disrupt a child's immune system and increase their risk of developing autoimmune diseases later in life .
Prevention and measures for adults
To reduce your risk of adult-onset type 1 diabetes:
- Whole Foods Diet : Eat a diet that is minimally processed and focuses on whole foods
- Reduce wheat intake : In particular, reduce the intake of refined modern wheat and choose whole wheat flour from ancient wheat or other grains (rice, millet, etc.)
- Avoid artificial sweeteners : Avoid artificial sweeteners whenever possible, and use small amounts of natural sweeteners if necessary.
- Improve intestinal environment : Actively consume fermented foods and dietary fiber to strengthen the intestinal barrier function
- Anti-inflammatory foods : Consuming foods containing omega-3 fatty acids and antioxidants suppresses excessive production of TNFα
- Regular health checks : If you have a family history, consider regular testing, including autoantibody testing.
From Kogaiko Shoten: Authentic Japanese Foods to Support a Healthy Body
Thank you for reading this far!
For those of you wondering, "So, what should I actually choose?", Kokako Shoten offers authentic foods and seasonings made using traditional Japanese methods, without the use of additives or chemicals.
Wheat-free staple food options

Gensenmai Series
The highest quality Koshihikari rice grown entirely on plant compost. This rice is grown using the power of nature without the use of pesticides or chemical fertilizers.
The pasta made with this spring rice is also delicious! The secret to its chewy texture is the addition of locally grown taro. Just like the spring rice, the taro is grown entirely in plant compost. Be sure to give it a try.

Joint Farm's roasted brown rice coffee is a healthy food, roasted for over 10 hours. It's gluten-free and caffeine-free. Its fragrant aroma makes it a great alternative to your morning coffee. It also has a warming effect. Brown rice coffee also has excellent detoxifying properties! And, it 's sweet, like soybean flour, made with Joint Farm's spring rice! Adding edible rice bran powder can also help smooth your morning bowel movements.
Fermented foods that improve your intestinal environment

This organic enzyme paste is made from domestically grown organic vegetables and fruits fermented for two years. It helps to improve your intestinal environment and normalize your immune system. One bottle lasts approximately two months. Gradually improve your intestinal environment and repair leaky gut.

Speaking of intestinal health, Jerusalem artichoke all-purpose powder is a must-have. Inulin feeds the beneficial bacteria in the intestines, producing short-chain fatty acids. Eating it in the morning also helps prevent blood sugar spikes. Unlike regular refined inulin, this powder is made from pesticide-free Jerusalem artichokes that are freeze-dried at low temperatures. It's also rich in vitamins, minerals, and dietary fiber, so we recommend making it a daily habit.
Related Article - Protect yourself from blood sugar spikes! Start a natural and healthy lifestyle with Aso's miracle "Jerusalem artichoke all-purpose powder"

MyGlut is a lactic acid bacteria that allows you to make homemade soy milk yogurt with live lactic acid bacteria. It supports intestinal health with plant-based lactic acid bacteria. Simply add it to unsweetened soy milk at room temperature for easy preparation. The plant-based lactic acid bacteria reach the intestines alive! You'll also get plant-based protein, so it's a two-for-one deal!
Support your immune system with the blessings of nature

Yaeyama Chlorella is made in Japan and is 100% pure! Born from the sunshine of Ishigaki Island, chlorella is packed with nutrients that will boost your body's basic strength. I've written about it many times before, but it's an essential base food for our household!
Related article - [Natural multivitamin] A thorough explanation of the amazing health benefits of Yaeyama Chlorella! [Detox]

Get total care with pure Japanese turmeric powder , made with four types of turmeric! It has excellent anti-inflammatory properties and is expected to suppress excessive production of TNFα. To enhance your body's natural healing ability, it makes more sense to consume turmeric in its natural form rather than refined ingredients!

Seaweed such as wakame, hijiki, and kelp! Seaweed is an extremely important food for preventing type 1 diabetes.
The water-soluble dietary fiber (alginic acid, fucoidan, etc.) that is abundant in seaweed helps repair the intestinal barrier that has been damaged by wheat, artificial sweeteners, and processed foods.
- Thickening of the mucosal layer : Promotes the production of mucus that protects the intestinal surface
- Suppresses inflammation in the intestinal wall : suppresses the production of inflammatory cytokines such as TNFα
- Normalizes intestinal permeability : Improves leaky gut syndrome
In other words, seaweed seals the holes in the intestines that wheat has forced open, helping to restore the intestines' natural barrier function.
And although the dietary fiber in seaweed cannot be broken down by our digestive enzymes, it is an excellent food source for the good bacteria in our intestines, producing a wealth of short-chain fatty acids!
Choose authentic seasonings
Don't underestimate the additives contained in seasonings. Because they are consumed every day, even a small amount can add up.
What's more, fake seasonings don't even go through the fermentation process. In other words, they are very unnatural foods in the eyes of nature.
Natural sea salt: Natural salt made using traditional methods. Authentic salt with a balanced mineral content.
Authentic vinegar made from organic rice. As a fermented food, it also helps improve the intestinal environment.
Authentic soy sauce brewed in traditional wooden barrels. No additives or preservatives are used.
summary
The influence of wheat, artificial sweeteners, and processed foods in the modern diet may be a major factor behind the onset of type 1 diabetes in adults. Wheat, in particular, increases intestinal permeability and induces the overproduction of inflammatory cytokines such as TNFα, which may be deeply involved in the mechanism by which the immune system mistakenly attacks pancreatic β cells.
The mechanisms by which these substances destroy the intestinal environment, cause chronic inflammation, and disrupt the immune system, triggering autoimmune reactions, are gradually being elucidated.From a preventative perspective, it is highly likely that a diet that chooses foods as close to natural as possible and avoids wheat and chemically synthesized additives will lead to a reduced risk of autoimmune diseases.
Health starts from the daily meals
At Kokako Shoten, we believe that choosing real food is the first step to good health.
"I don't want people to regret it after they get sick." With that thought in mind, I work every day to spread the word.
Nowadays, when you walk outside, you are faced with food full of additives and chemicals. That is why each individual needs to be able to discern what is being consumed.
Why not start filling your table with real ingredients little by little starting today?
Kokako Shoten delivers authentic Japanese food to you wherever you are in the world. We wholeheartedly support your healthy daily life!
Click here for the Kokaiko Shoten online store
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